Dapoxetine Hydrochloride CAS 129938-20-1
Dapoxetine Hydrochloride CAS 129938-20-1
(S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride, S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C21H23NO·HCl = 341.88 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 129938-20-1 |
| Reaxys Registry Number | 10603966 |
| PubChem Substance ID | 253660535 |
| Merck Index (14) | 2821 |
| MDL Number | MFCD08272809 |
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 179.0 to 183.0 °C |
| Specific rotation [a]20/D | +124 to +129 deg(C=1, MeOH) |
| NMR | confirm to structure |
| Melting Point | 181 °C |
| Specific Rotation | 125° (C=1,MeOH) |
| Solubility (soluble in) | Methanol |
Description:
Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.
Biochem/physiol Actions:
Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe.
Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation
Potent and selective SSRI
Features and Benefits:
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates
Application
ORID products are tested extensively in-house and supplied worldwide to the Life Sciences industries.
Related Products
ORID products are tested extensively in-house and supplied worldwide to the Life Sciences industries.
Company Profile
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