Fmoc-Asn(Trt)-OH CAS 132388-59-1
Fmoc-Asn(Trt)-OH CAS 132388-59-1
Nα-(9-Fluorenylmethoxycarbonyl)-Nγ-trityl-L-asparagine, Nα-Fmoc-Nγ-trityl-L-asparagine
| Empirical Formula (Hill Notation): | C38H32N2O5 |
| CAS Number: | 132388-59-1 |
| Molecular Weight: | 596.67 |
| Beilstein: | 4343823 |
| MDL number: | MFCD00077049 |
| UNSPSC Code: | 12352209 |
| eCl@ss: | 32160406 |
| PubChem Substance ID: | 57651076 |
| NACRES: | NA.26 |
| Product Name | Fmoc-Asn(Trt)-OH, ≥97.0% |
| Assay | ≥97.0% |
| form | powder |
| optical activity | [α]20/D −15.0±1°, c = 1% in methanol |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| mp | 201-204 °C (lit.) |
| application(s) | peptide synthesis |
| functional group | Fmoc |
| storage temp. | 2-8°C |
| SMILES string | OC(=O)[C@H](CC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46 |
| InChI | 1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1 |
| InChI key | KJYAFJQCGPUXJY-UMSFTDKQSA-N |
Description:
Fmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection .
Application:
Fmoc-Asn(Trt)-OH has been used to synthesize peptides on cellulose membrane by SPOT method.
Application
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Related Products
ORID products are tested extensively in-house and supplied worldwide to the Life Sciences industries.
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